Medical
Understanding Obesity Part 1: Diagnosis & Treatment

What we’ll cover:

  • Obesity as a complex disease
  • Understanding BMI
  • The various factors that impact Obesity
  • Treatment of Obesity

Obesity is a significant public health issue in the UK, affecting millions of people and contributing to chronic conditions like type 2 diabetes, heart disease, and joint problems. Managing obesity requires recognising it as a complex and ongoing condition influenced by genetics, environment, psychological factors, and socioeconomic challenges. These factors go beyond personal responsibility, making a compassionate, patient-centred approach essential for effective care.

Understanding BMI and Its Limitations

Body Mass Index (BMI) is a common way to assess obesity. It calculates weight in kilograms divided by height in metres squared (kg/m²). For most adults, the categories are:

  • 18.5 to 24.9 is considered a healthy weight
  • 25 to 29.9 may indicate overweight
  • 30 or above may indicate obesity
  • 40 or above may indicate severe obesity

While BMI is widely used, it has limitations. It doesn’t account for differences in muscle mass, fat distribution, or ethnicity. For example:

  • People with higher muscle mass may have a higher BMI without excess body fat.
  • Visceral fat (around internal organs) poses a higher health risk than subcutaneous fat (under the skin).
  • People from ethnic minority backgrounds may face a greater risk of conditions like type 2 diabetes at lower BMI levels.

To provide a clearer picture of health risks, healthcare professionals often use additional measures, such as waist circumference, alongside BMI.

The Complex Causes of Obesity

Obesity is not simply a matter of eating too much or exercising too little. It is influenced by many interconnected factors:

  • Genetics: Genes can affect appetite, metabolism, and fat storage, playing a significant role in body weight.
  • Environment: Modern lifestyles often promote sedentary behaviour and easy access to calorie-dense, low-nutrient foods, making weight management harder.
  • Socioeconomic Factors: Limited access to nutritious food, safe spaces for exercise, and healthcare support can make weight management more challenging for people in disadvantaged communities.
  • Psychological Factors: Mental health, stress, and emotional eating can affect food choices and activity levels. Addressing these often requires psychological support alongside other routine medical care.
  • Cultural Influences: Cultural attitudes towards weight, health, and body image can shape behaviours and impact care approaches.
  • Biological Responses: The body’s natural response to weight loss, such as slowing metabolism and increasing hunger signals, makes maintaining weight loss difficult over time.

Treatment

In the UK, obesity treatment follows a tiered approach, starting with lifestyle changes and progressing to medical or surgical options when needed.

  1. Lifestyle Interventions:
    Programmes like Roczen focus on long-term lifestyle changes, including:
    • Tailored diet plans
    • Exercise guidance
    • Behavioural support provided by nurses, dietitians and psychologists
  2. Medications:
    When lifestyle changes alone aren’t enough, medications can support weight loss by targeting appetite, metabolism, or fat absorption. Examples include:
    • GLP-1 and GIP receptor agonists (e.g., Wegovy, Mounjaro): These mimic natural hormones released after eating to regulate appetite and slow digestion, enhancing fullness. These are only to be used alongside lifestyle interventions, with a reduced calorie intake and increased physical activity.
    • Fat absorption inhibitors (e.g., Orlistat): These reduce the absorption of dietary fat.
    • Combination medications (e.g., Phentermine-Topiramate): These work on appetite control and cravings, often helpful for emotional eating.
  3. Bariatric Surgery:
    For people with severe obesity (BMI ≥40 or BMI ≥35 with related health conditions), surgical options like gastric bypass or sleeve gastrectomy can lead to significant and sustained weight loss. These procedures also improve obesity-related health issues and quality of life.

Summary

Obesity is a complex condition shaped by genetic, environmental, psychological, and socioeconomic factors. It cannot be understood solely through BMI, as other measures and personalised care are often needed. Effective treatment requires a compassionate, individualised approach, combining lifestyle interventions, medical therapies, and, where necessary, surgical options. Roczen’s programme is designed to support sustainable, long-term weight management with dietary, physical activity and medication interventions, helping patients achieve better health and wellbeing.

December 12, 2024
Written by
Tiago Grohmann
Reviewed by
Dr. Laura Falvey

References

NHS. (2020). Obesity: Causes, diagnosis and treatment. https://www.nhs.uk/conditions/obesity/

Dobbie, L. J., Coelho, C., Crane, J., & McGowan, B. (2023). Clinical evaluation of patients living with obesity. Internal and emergency medicine, 18(5), 1273–1285. https://doi.org/10.1007/s11739-023-03263-2

Patient Advocate Foundation. (2021). Best practices in patient advocacy. https://www.patientadvocate.org/best-practices/

https://www.nihr.ac.uk/patient-and-public-involvement-and-engagement-resource-pack-senior-investigators

This link is only accessible via the Roczen app